Cytomegalovirus (CMV) Ab, IgM

Alternate Name: CMV_IgM

  | Human cytomegalovirus IgM (hCMV IgM)

SAL Code:






Turn Around Time:

1 Day






Diagnostic Immunology

Performing Laboratory:

Sherman Abrams Laboratory


Chemiluminescent Immunoassay (CLIA)

Specimen Requirements:

Primary Tube:


Primary Substance:


Alternate Sample Info:

Strict SST



Stable Ambient:

14 Days

Stable Fridge:

14 Days

Stable Frozen:

14 Days

Rejection Criteria:

Gross hemolysis; lipemia; improper labeling

Clinical Info:

This assay is designed for the qualitative determination of IgM antibodies to human cytomegalovirus (hCMV) in human serum. It is intended to be used as an aid in the diagnosis of acute CMV infection.

Additional Information:

Human cytomegalovirus (hCMV) is a herpes virus. It is ubiquitous, species-specific, and can be spread by close human contact. Primary infection may be acquired through different transmission routes and in different periods of life (e.g., congenital, perinatal, and post-natal infections). Following primary infection, hCMV enters a latency phase during which the virus can be found in B lymphocytes. Subsequent reactivation of viral replication (secondary infection) may take place concomitantly with changes in the relationship between host and virus. Reinfection with exogenous virus can occur in subjects with deficiency of cellular immunity, even when antibodies to hCMV are already present.

Sample Collection:

Collect patient samples using standard phlebotomy techniques. Click here for additional collection instructions.

Test Limitations:

The clinical diagnosis must be interpreted with clinical signs and symptoms of the patient. The results of this assay are not by themselves diagnostic and should be considered in association with other clinical data and patient symptoms.

Results from immunosuppressed patients should be interpreted with caution.

Screening of the general population should not be performed. The positive predictive value depends on the likelihood of the virus being present. Testing should only be performed on patients with clinical symptoms or when exposure is suspected.

IgM responses may persist for weeks to months post-infection. Low levels of IgM may be detectable during the reactivation phase of infection. This test is intended for qualitative determination only.

Test Information: